Determinación de la potencia antimicrobiana por el método Turbidimétrico. Antimicrobial potency assessment using the turbidimetric method.

Abstract

The pharmaceutical industry is an essential sector within life

science, facilitating the development of new drugs and

technologies aimed at human and animal health. The quality

of pharmaceutical products must be guaranteed through

systematic evaluation processes that ensure both their

efficacy and safety; in this context, the assessment of

microbiological methods becomes an essential component

within the quality control laboratory. The objective of this

research was to determine the antimicrobial potency of an

injectable pharmaceutical product with oxytetracycline as the

active ingredient using the Turbidimetric method, as well as

to design and validate the methodology. The methodology

used refers to the general analysis method 0100,

microbiological assay of antibiotics from the Mexican

Pharmacopoeia. In this study, the antimicrobial potency

obtained for the veterinary injectable pharmaceutical product

with Oxytetracycline was 109.91%, which is acceptable. This

result confirms that the drug inhibits the growth of the test

microorganism, Staphylococcus aureus (ATCC 29373). By

implementing this validated method, the reliability of the

results is guaranteed.